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Clinical aspects of TB
Radiographic
appearances of pulmonary tuberculosis :.
There are no
definitive radiographic appearances of tuberculosis. Classically,
tuberculosis affects the apices and upper zones more frequently
than other areas of the lung fields. Lesions may appear as small
nodules or patchy infiltration which may be unilateral or bilateral.
The best radiographic view to see the apices clearly, without bony
structures in the way, is the apical lordotic view. If the
disease heals, calcified lesions may appear in the lung and ipsilateral
hilar nodes.
If the disease
progresses a larger area of pneumonia will develop and there may
eventually be cavity formation. Cavities
in the upper zones are common in tuberculosis. Their appearance
is a classical sign. However, it is important to remember that there
are other cavitating pneumonias, for example staphylococcus, klebsiella
and some anaerobic streptococci.
Once cavitation
has occurred in tuberculosis, there is a high risk of bronchopneumonic
spread to other parts of the lung where bacilli are inhaled to other
lung segments. When this occurs, tuberculous bronchopneumonia
develops and the radiographic appearances are those of extensive
unilateral or bilateral soft opacities. These findings are indistinguishable
from severe bacterial bronchopneumonia or aspiration pneumonia,
except that cavities may be obvious in tuberculosis.
Pleural
effusions may develop and can be massive in tuberculosis: apical
shadows of pulmonary tuberculosis may be present, usually in the
ipsilateral lung.
Tuberculomas
may appear as dense, discrete, rounded nodules which may or may
not calcify. The obvious differential diagnosis is lung cancer.
Histological examination is advisable, either by bronchoscopy, per-cutaneous
needle biopsy or thoracotomy. Remember that adenocarcinoma of lung
may occur in non-smoking young patients, particularly females, in
Hong Kong.
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