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Clinical aspects of TB
Clinical
presentation
Extrapulmonary
tuberculosis
Miliary
tuberculosis :.
This occurs
following widespread haematogenous dissemination of tubercle bacilli.
If the pulmonary artery is involved, spread is limited to lung.
If pulmonary vein is involved, spread is systemic.
Onset in the
young is usually acute whereas in the elderly it is insidious. General
symptoms are fever, weakness, malaise, loss of weight, dry cough
and breathlessness. Alternatively, the presenting symptoms may be
those of associated tuberculosis meningitis: gradual onset listlessness
or irritability, headache and sometimes seizures or cranial nerve
abnormalities.
A pathognomonic
sign is the presence of choroidal tubercles. Chest X-ray classically
shows uniformly distributed nodules but may be normal.
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