Microencapsulation is the process to entrap cells within the confines of a semi-permeable membrane or a homogenous solid matrix.
A collagen-based microencapsulation technology has been developed to entrap cells within a dense meshwork of nano-sized collagen fibers.
This meshwork is able to support growth and proliferation, migration and differentiation of cells. Many cell types including
mesenchymal stem cells, embryonic stem cells, chondrocytes and fibroblasts have been successfully encapsulated.
The collagen-cell microspheres are being developed for tissue engineering applications.